Patient Variability Seldom Assessed in Cost-effectiveness Studies

Using propensity score methods to analyse individual patient‐level cost‐effectiveness data from observational studies

Cost, effectiveness, and cost-effectiveness.

Incremental or marginal cost-effectiveness ratios are founded on a number of assumptions that weaken their suitability as a way to balance competing economic and clinical priorities. We therefore propose a more relevant and responsible way to gauge the impact of clinical management strategies based on “consumer protection” principles—explicit disclosure of (1) the total magnitude of expected be...

Including Patient Choice in Cost- Effectiveness Decision Rules

Ec co on no om mi ic cs s a an nd d D De ec ci is si io on n S Sc ci ie en nc ce e D Di is sc cu us ss si io on n P Pa ap pe er r S Se er ri ie es s Abstract There has been increasing discussion in the economic literature, about the appropriateness of using general population values within technology appraisal. This paper proposes an alternative approach to incorporating patient values into the...

Bias in published cost effectiveness studies: systematic review.

OBJECTIVE To investigate if published studies tend to report favourable cost effectiveness ratios (below 20,000 dollars, 50,000 dollars, and 100,000 dollars per quality adjusted life year (QALY) gained) and evaluate study characteristics associated with this phenomenon. DESIGN Systematic review. Studies reviewed 494 English language studies measuring health effects in QALYs published up to De...

A review of cost-effectiveness studies in ovarian cancer.

BACKGROUND Ovarian cancer is the fifth leading cause of all cancer-related deaths among women. While the costs of diagnosis and treatment impact the affected individual and the health system, the most important costs for the patient are often the pain and suffering associated with ovarian cancer. The quality of life associated with any management decision should be closely examined. Cost-effect...